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18-[(2-Methyl-2-propanyl)oxy]-18-oxooctadecanoic acid CAS-No-843666-40-0

CAS NO.:843666-40-0

White to Almost white powder to crystal ; Purity 99%          MF: C22H42O4         MW: 370.57

18-(tert-Butoxy)-18-oxooctadecanoic Acid is a synthetic intermediate used in the preparation of semaglutide. It can be produced by the catalysis of 18-hydroxyoctadecanoic acid by ethyl bromoacetate in the presence of formamide and magnetic trifluoroacetic acid.

***Product capacity from hundreds of KGs to Tonnage. Stable supplying at high quality. ISO quality system.

Melting point  68 °C
Boiling point  470.7±18.0 °C(Predicted)
density  0.950±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka 4.78±0.10(Predicted)
form  Solid
color  White to Off-White
Purity 99% 
Safety info  Non-DG
Product manager  Joy Wu; Email: Joy@coreychem.com
  • 18-(tert-Butoxy)-18-oxooctadecanoic Acid is a synthetic intermediate used in the preparation of semaglutide. It can be produced by the catalysis of 18-hydroxyoctadecanoic acid by ethyl bromoacetate in the presence of formamide and magnetic trifluoroacetic acid.
  • 18-(tert-Butoxy)-18-oxooctadecanoic Acid is used to engineer long-acting, potent exendin-4 based GLP-1 analog for microstructure-based transdermal delivery for glycemic control.
  • 18-(tert-Butoxy)-18-oxooctadecanoic acid) is a short linker featuring a carboxylic acid and a tert-butyl ester. Carboxylic acids can be reacted with alcohols or amines, while the tert-butyl ester can be deprotected and further connected to another molecule.It is a pharmaceutical intermediate ingredient used in the preparation of somatostatin. It also has catalytic activity.

CONTACT/Email address: Joy@coreychem.com

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