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1,3-DIIODOBENZENE CAS NO.: 626-00-6

CAS NO.:626-00-6
Product Name: 1,3-DIIODOBENZENE
CAS No.: 626-00-6 
Form: Pale yellow liquid or solid
Product Name: 1,3-DIIODOBENZENE
Synonyms: 1,3-diiodo-benzen;Benzene, 1,3-diiodo-;Benzene, m-diiodo-;benzene,1,3-diiodo-;Benzene,m-diiodo-;M-DIIODOBENZENE;1,3-DIIODOBENZENE;1,3-diiodo-benzen、1,3-diiodobenzene、m-Diiodobenzene、1,3-diiodo-benzene、1,3-Dijodbenzol
CAS: 626-00-6
MF: C6H4I2
MW: 329.9
EINECS: 210-921-1
Structure:
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1,3-Diiodobenzene (CAS No. 626-00-6)

Q1: What is it? What are its key properties?

1,3-Diiodobenzene, also known as m-Diiodobenzene, is an iodine-containing aromatic compound widely used as an intermediate in organic synthesis.

Key properties:

  • Product Name: 1,3-Diiodobenzene
  • CAS No.: 626-00-6
  • Molecular Formula: C₆H₄I₂
  • Molecular Weight: 329.90 g/mol
  • Appearance: White to light yellow crystalline solid
  • Melting Point: Approximately 34–37°C
  • Water Solubility: Insoluble in water
  • Physical Form: Solid at normal room temperature, but it may soften or melt at elevated temperatures.

Due to its relatively low melting point, temperature control should be considered during storage and transportation.

Q2: What is it used for?

1,3-Diiodobenzene is mainly used as an organic synthesis intermediate.

Typical applications include:

  • Organic synthesis
  • Cross-coupling reactions, such as Suzuki coupling
  • Pharmaceutical intermediate synthesis
  • Agrochemical intermediate synthesis
  • Synthesis of fine chemicals and functional materials

The two iodine atoms provide useful reaction sites for further functionalization and coupling reactions.

Q3: Solid form or aqueous solution — which should I choose?

The solid form is recommended.

1,3-Diiodobenzene is insoluble in water, so it is normally supplied and used as a solid rather than as an aqueous solution.

If a solution is required for a specific application, an appropriate organic solvent may be considered depending on the customer’s reaction system and process requirements.

For commercial quantities, the product is generally supplied as a solid crystalline material in suitable sealed packaging.

Q4: What precautions apply when handling it?

Appropriate personal protective equipment should be used when handling 1,3-Diiodobenzene.

Recommended precautions include:

  • Wear appropriate protective gloves.
  • Wear safety goggles or suitable eye protection.
  • Avoid inhalation of dust.
  • Avoid direct contact with skin and eyes.
  • Handle in a well-ventilated area.
  • Wash hands thoroughly after handling.
  • Keep the material away from strong oxidizing agents.

Please refer to the latest Safety Data Sheet (SDS) for detailed hazard classification and handling requirements.

Q5: How should it be stored and transported?

Storage:

  • Store in a cool, dry and well-ventilated place.
  • Keep the container tightly closed.
  • Protect from direct sunlight and excessive heat.
  • Refrigerated storage, such as 2–8°C, may be recommended depending on the product specification and supplier’s SDS.
  • Avoid prolonged exposure to temperatures above its melting point of approximately 34–37°C.

Transportation:

The product should be transported in secure, tightly sealed and suitable packaging. Exposure to excessive heat and direct sunlight should be avoided, especially during warm-weather transportation.

Please note that the recommended storage temperature and the regulatory transportation requirements are not necessarily the same. The actual transportation conditions should be confirmed based on the latest SDS, product specification, packaging configuration, transportation route, and carrier requirements.

For international shipments, the applicable transportation classification and documentation should be confirmed with the relevant logistics provider before shipment.

Q1: What is the main application of this product?

1,3-Diiodobenzene (CAS No. 626-00-6) is mainly used as an intermediate for organic synthesis.

Its two iodine atoms provide reactive sites for further functionalization and cross-coupling reactions. It can therefore be used as a building block for the synthesis of various specialty chemicals, pharmaceutical intermediates, agrochemical intermediates, and functional materials.

Q2: In which end products are these downstream products used?

The downstream products derived from 1,3-diiodobenzene can be used in various specialty chemical applications, depending on the subsequent synthetic route.

Potential areas include:

  • Pharmaceutical and pharmaceutical intermediate synthesis
  • Agrochemical-related intermediates
  • Specialty and fine chemicals
  • Functional organic materials
  • Research and development applications

The specific end use depends on the customer’s downstream synthesis and the final molecular structure.

Q3: What are its key advantages?

The key advantage of 1,3-diiodobenzene is its two reactive iodine substituents positioned at the 1,3-positions of the benzene ring.

This structure provides:

  • Two useful reaction sites for further functionalization
  • Good versatility as a synthetic building block
  • Suitability for various cross-coupling and substitution reactions
  • Flexibility for the preparation of more complex aromatic compounds

Q4: Are there applications beyond personal care?

Yes. 1,3-Diiodobenzene is not limited to personal care applications.

It is primarily an intermediate for chemical synthesis and can be used in areas such as pharmaceuticals, agrochemicals, specialty chemicals, functional materials, and other research or industrial synthesis applications.

Q5: What practical value does it bring to formulations?

1,3-Diiodobenzene itself is not typically used as a direct formulation ingredient. Its practical value is mainly as a synthetic building block for producing downstream compounds.

Therefore, its contribution to a final formulation depends on the properties and function of the downstream compound synthesized from it. It should not be considered a conventional surfactant, emulsifier, or direct formulation additive.

 

 

Package: 5 kg per fluorinated bottle
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