1,2-Dioleyloxy-3-dimethylamino-propane (DODMA)

CAS NO.：104162-47-2

Appearance: Colorless to slight yellow liquid

Purity: ≥98%

Product name	DODMA
Synonym	1,2-Dioleyloxy-3-(dimethylamino)propane;2,3-Dioleyloxy-1-(dimethylamino)propane;DODMA;N,N-Dimethyl-2,3-bis[(9Z)-9-octadecen-1-yloxy]-1-propanamine;2-amino-2,3-dimethylChemicalbookoleanol;1,2-Dioleyloxy-3-dimethylamino-propane(DODMA);1-Propanamine,N,N-dimethyl-2,3-bis[(9Z)-9-octadecen-1-yloxy]-;2,3-Dioleyloxy-1-(dimethylamino)propane>=98.0%(TLC)
CAS No.	104162-47-2
MF	C41H81NO2
MW	620.09
Related categories	Pharmaceutical excipient; Lipid
Storage	Storage at 2-8℃
Packaging	1kg/bottle 5kg/bottle, 25kg/drum, can be also subpacked as customer’s request.
Product Manager	Cara Lee Email: Cara@coreychem.com

1,2-Dioleoyl-3-dimethylamino-propane (DODMA) is a crucial functional material widely used in the fields of gene therapy and drug delivery. Its core application is as an ionizable cationic lipid, enabling the construction of highly efficient nano-delivery systems.

The application is as below:

Lipid Nanoparticle (LNP) Excipient：Key cationic lipid for mRNA vaccines and siRNA/miRNA drugs; encapsulates, protects nucleic acids, and facilitates cellular internalization.
Gene Transfection Vector：Forms cationic liposomes for efficient delivery of plasmid DNA and CRISPR/Cas9 components; used in in vitro/in vivo gene transfection and therapy。
Drug Delivery System：Combines with phospholipids to encapsulate negatively charged small molecules, proteins, and peptides; enhances stability and delivery efficiency。
Biomembrane Model Research：Mimics the cationic lipid environment of cell membranes; constructs membrane models for studying membrane protein function and biomolecular interactions。
Targeted Delivery Formulations：Conjugates with targeting ligands (antibodies, peptides) for targeted drug transport and reduced toxicity。
Cell Labeling and Imaging：Associates with fluorescent probes/magnetic particles for long-term cell labeling, tracking, and bioimaging。
Biosensor Construction：Couples with enzymes/antibodies to develop biosensors for nucleic acid/protein detection。

★Our Superiority:

1. Factory direct supply, Competitive price in china market, long-term supply and adequate inventory.

2. Production Capacity: 500KG per month, also can adjust the production quantity according to the customer’s demand.

3. With stable quality and competitive price, Supplying this product to the markets of the United States, The south Korea and Europe etc for an extended period of time. And would like to supply free sample to our every customer.

4. Providing Certificate Of Analysis (COA), Material Safety Data Sheet (MSDS).

5. After-sale service: Timely after-service resolves your worry for international trade. If you have problem about the quality, we will arrange refunds in time.

❤ The customer would like to think, do the customers, to the customers:

Quick Response Within 12 hours.
Free from after-sale worries: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China.
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Any interest, welcome to contact: cara@coreychem.com

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1,2-Dioleyloxy-3-dimethylamino-propane (DODMA)

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