1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE

1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE (CAS: 56421‑10‑4), commonly referred to as a mixed glycerophospholipid, belongs to the phosphatidylcholine (PC) class of lipids. Its main functions are:

1. Component of Lipid Nanoparticles / Liposomes

   • As a structural phospholipid, it can be used to prepare liposomes or lipid nanoparticles (LNPs).

   • Provides a bilayer structure in lipid membranes, helping to encapsulate and protect drugs or nucleic acids.

2. Enhancing Membrane Stability and Fluidity

   • The combination of saturated and unsaturated fatty acid chains (C18:0 and C18:1) gives the membrane moderate fluidity and stability, which benefits the stability of drug delivery systems.

3. Biocompatibility and Low Toxicity

   • As a natural phospholipid derivative, it has high biocompatibility and can be used in in vivo drug delivery systems with low toxicity.

4. Supporting Drug or Gene Delivery

   • When combined with cationic lipids or other helper lipids, it can be used in gene delivery vectors, mRNA vaccines, or liposomal drug formulations to improve delivery efficiency.

In summary: This compound primarily acts as a lipid carrier component, used to construct lipid membranes or lipid nanoparticles, enhancing the delivery efficiency and stability of drugs or nucleic acids.

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