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Pneumocandin B0

December 8, 2025

Product Name: Pneumocandin B0

CAS: 135575-42-7

Safety Information:
Hazardous information: No DG
HS Code: 2933990099

Packing: Multiple packaging options available, customizable as per your requirements.

Items  Specifications 
Appearance    White to light yellow powder
Assay ≥95.0%
Molecular Formula​ C₅₀H₈₀N₈O₁₇
Molecular Weight​ 1065.21
Storage
Store in a cool, dry, and well-ventilated place. Keep away from light and moisture. Ensure the container is tightly sealed.

What is Nymocandin B0?

Pneumocandin B0 is a cyclic lipopeptide compound naturally synthesized by the filamentous fungus *Glarea lozoyensis*, first discovered in the 1990s. Its molecular structure contains a cyclic hexapeptide core and fatty acid side chains, exhibiting unique chemical properties. Industrially, strain optimization through UV mutagenesis, chemical mutagenesis, and CRISPR-Cas9 gene editing has significantly increased yield and reduced impurity content. As a key intermediate in the synthesis of caspofungin, Pneumocandin B0 plays a vital role in biological research and development. Advances in its production technology have driven the development of related industrial chains, making it a typical case study in fungal metabolism and synthetic biology.

The production process of Numocontin B0 is as follows:

Fermentation: Optimize the culture medium and conditions to produce the target compound through fungal fermentation.

Pretreatment: Centrifuge to separate the mycelium, and perform preliminary extraction using organic solvents.

Preliminary purification: Remove pigments using activated carbon adsorption, followed by washing with water to remove polar impurities.

Fine purification: Further purify using resin chromatography with gradient elution.

Crystallization and drying: Concentrate the solution, crystallize, and then dry to obtain the finished product.

Uses:

1. Biological Project Development: Primarily applied to biological and life science research projects, project development, and cutting-edge biological technologies.

2. Experimental Detection and Analysis: Biological data detection and analysis, and database model construction and validation.

3. International Trade: Supplying foreign research institutions for project development, academic experience exchange, and new product development by overseas end-product biotechnology companies through foreign trade exports.

Advantages in specifications: Complete range of packaging options including bottles, bags, and barrels
Quality assurance: High-quality research-grade craftsmanship, complete technical documentation and certificates

Contact Manager Email:Nicole@coreychem.com

 

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