Piperazine (CAS 110-85-0): Synthesis and Application of Fluorinated Horner Reagent with Full Analysis
1、 Product Overview
Piperazine is a cyclic diamine and an important nitrogen-containing organic intermediate, also known as 1,4-Diazacyclohexane or Tetramethylenediamine.
Its key value comes from its stable six-membered ring structure containing two nitrogen atoms, good water solubility, and versatility as a building block for pharmaceutical intermediates, specialty chemicals, and other nitrogen-containing compounds.
Piperazine is widely used in organic synthesis and pharmaceutical-related manufacturing and is suitable for both research and industrial applications.
2、 Basic Product Information
Product Name: Piperazine
Synonyms:
1,4-DIAZACYCLOHEXANE;PIPERAZINE
CAS NO.: 110-85-0
Molecular Formula: C4H10N2
Structural formula：
Molecular Weight: Approximately 86.14 g/mol
Appearance: White flakes
Odor: Characteristic amine odor
Water Solubility: Soluble in water
Main Function: Pharmaceutical intermediate / organic synthesis intermediate / nitrogen-containing building block
Product Manager: Cherry Zhu
Email: Cherry@coreychem.com
3、 Frequently Asked Questions (FAQ)
1) What is Piperazine and what are its key characteristics?
Piperazine is a cyclic diamine with two nitrogen atoms in a six-membered ring.
Its molecular structure provides good chemical versatility, making it an important intermediate for the synthesis of pharmaceutical compounds, specialty chemicals, and various piperazine derivatives.
It is generally supplied as a white crystalline solid and is soluble in water.
2) What are the main applications of Piperazine?
Piperazine is mainly used as an organic synthesis and pharmaceutical intermediate.
Its major application fields include:
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Pharmaceutical intermediate synthesis
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Organic synthesis
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Specialty chemical manufacturing
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Preparation of piperazine derivatives
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Chemical research and development
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Synthesis of nitrogen-containing compounds
Its main value is its versatile diamine structure, which allows further chemical modification.
3) Why is Piperazine important in pharmaceutical synthesis?
The piperazine ring is a common structural component in pharmaceutical chemistry.
Piperazine can be used as a building block or intermediate for preparing various active pharmaceutical compounds and pharmaceutical intermediates.
Its two nitrogen atoms provide useful sites for chemical modification and allow the preparation of a wide range of substituted piperazine derivatives.
4) What are the advantages of your Piperazine supply?
We focus on providing consistent quality, stable supply, and reliable batch-to-batch performance.
Our advantages include:
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Mature production process and established quality control.
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Stable inventory to support regular and bulk requirements.
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Consistent product specifications between batches.
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Long-term cooperation experience with customers.
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Reliable supply capability for recurring orders.
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Flexible packaging options according to customer requirements.
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Professional support for COA, SDS, specifications, and order coordination.
5) What should be considered when handling and storing Piperazine?
Piperazine should be handled according to the applicable SDS and local safety requirements.
Keep the container tightly sealed and store it in a cool, dry, and well-ventilated area. Protect the product from excessive moisture, heat, contamination, and incompatible materials.
During handling, avoid unnecessary generation of dust and use appropriate personal protective equipment.
4、 Application Cases
1) Pharmaceutical Manufacturing – Pharmaceutical Intermediate
Piperazine is widely used as an important intermediate and building block in pharmaceutical synthesis.
Its cyclic diamine structure can be incorporated into various pharmaceutical molecules and used to prepare substituted piperazine intermediates.
2) Organic Synthesis – Nitrogen-Containing Building Block
Piperazine can be used as a versatile nitrogen-containing building block in organic synthesis.
It can undergo further functionalization at its nitrogen atoms to produce a variety of derivatives for chemical research and manufacturing.
3) Specialty Chemicals – Piperazine Derivatives
Piperazine is used as a starting material for the preparation of substituted piperazines and other specialty chemicals.
Its well-established chemistry makes it suitable for different synthesis routes and downstream chemical applications.
4) Chemical Research – Synthetic Intermediate
Piperazine can be used in laboratory and industrial research as a defined cyclic diamine intermediate.
It supports the development and synthesis of new nitrogen-containing compounds and functional organic molecules.
5) Pharmaceutical Research – Structure Modification
Piperazine can be incorporated into molecular structures during pharmaceutical research to support the development of compounds with different physicochemical and structural characteristics.
It is therefore commonly encountered in medicinal chemistry and pharmaceutical intermediate development.
5、 Safety and Storage
Store Piperazine (CAS NO.: 110-85-0) in a cool, dry, and well-ventilated area and keep the original container tightly sealed.
Protect the product from excessive moisture, heat, direct sunlight, contamination, and incompatible materials.
As Piperazine is supplied as a crystalline solid or powder, avoid unnecessary dust generation during weighing and transfer. Appropriate ventilation and personal protective equipment should be used during handling.
6、Product Manager Information
Product Manager: Cherry Zhu
Email: Cherry@coreychem.com
