Palladium (II) Acetate is one of the most widely used palladium salts among platinum-group metal catalysts, with catalytic activity second only to platinum catalysts. As a typical palladium salt soluble in organic solvents, it is extensively employed to initiate or catalyze a broad range of organic synthesis reactions, making it an indispensable reagent in modern organic synthesis, pharmaceutical manufacturing, and materials science.
Basic information:
| Chemical Name | Palladium (II) Acetate |
| Synonyms | ACETIC ACID PALLADIUM(II) SALT |
| CAS No. | 3375-31-3 |
| Molecular Formula | Pd(CH3COO)2 |
| Molecular Weight | 224.51 |
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Specification:
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Items |
Specifications |
Test Result |
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Appearance |
Yellow-red powder crystal |
Conform |
|
Purity |
≥98% |
Conform |
|
Assay/Pd |
≥47.4% |
Conform |
|
Solubility |
Take a certain amount of palladium acetate, add glacial acetic acid, after heating and dissolving, the solution should be clarified |
Conform |
|
Conclusion |
This product conform to the above specifications |
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Storage condition: |
Sealed and kept in cool and dry place away from dampness. |
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Core Use of Palladium (II) Acetate CAS No.: 3375-31-3:
Cross-Coupling Catalysis
Pd(OAc)2 is the catalyst or precursor of choice for the major named cross-coupling reactions that build C–C and C–N bonds.
Key Application Areas:
- Pharmaceuticals & API synthesis — Critical C–C / C–N bond-forming steps for anticancer agents, cardiovascular drugs, antivirals, and antibiotics. The 2010 Nobel Prize in Chemistry recognized this catalysis platform.
- Fine chemicals — Alkene functionalization, C–H activation, carbonylation, and aerobic oxidation of alcohols (green alternative to Cr-based oxidants).
- Industrial catalysis — Vinyl Acetate Monomer (VAM) production from ethylene + acetic acid; cyclohexanone / adipic acid / caprolactam processes (nylon value chain).
- Nanomaterials & electronics — Precursor for Pd nanoparticles, fuel cell catalysts (PtPdCu alloys), supercapacitor electrodes, nanoelectronic devices, and Pd electroplating baths.
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