Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent containing an azide group that enables highly efficient biomolecular coupling.
- Basic information
- English name: Lys(MMT)-PAB-oxydiacetamide-PEG8-N3
- CAS number: 1224601-12-0
- Molecular formula: C55H77N7O14
- Molecular weight:1060.26
- Related categories: Fine Chemicals
- Transport Information: Not dangerous goods
- Application
- Antibody-Drug Conjugate (ADC) Development
Serves as a cleavable linker for conjugating highly potent cytotoxic drugs to targeting antibodies, enabling precise cancer-targeted therapy. The PEG8 chain enhances the solubility of the conjugate and minimizes aggregation.
- Click Chemistry & Bioconjugation
The terminal azide group (N3) enables efficient cycloaddition reactions (CuAAC or SPAAC) with alkyne-containing molecules, facilitating the construction of complex biomolecular structures or the attachment of fluorescent probes, among other applications.
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