Liraglutide CAS No.: 204656-20-2 a long-acting GLP‑1 receptor agonist and a synthetic analog of human glucagon‑like peptide‑1. It shares high sequence homology with native GLP‑1 and offers stable, prolonged action in the body.
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📋Basic information:
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Product Name: |
Liraglutide |
CAS NO: |
204656-20-2 |
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Molecular Formula: |
C172H265N43O51 |
Molecular Weight: |
3751.202 |
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Sequence: |
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(Pal-y-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
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📌Specification:
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Items |
Specifications |
Test Result |
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Appearance |
White or almost white powder |
White powder |
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Molecular |
3751.2±2 |
Conform |
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Purity(HPLC) |
≥99.0% |
99.0% |
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Related substances (HPLC)
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Maximum single impurrities≤0,5% Total impurities≤1.0% |
0.3% 1.0% |
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Bacterial Endotoxins |
<10 EU/mg |
Conform |
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Amino Acid Content |
Asp:0.9-1.1 Ser:2.7-3.3 Glu:4.5-5.5 Gly:3.6-4.4 His:0.9- 1.1 Arg:1.8-2.2 Thr:1.8-2.2 Ala:3.6-4.4 Tyr:0.9- 1.1 Val:1.8-2.2 Lys:0.9-1.1 Ile:0.9-1.1 Leu:1.8-2.2 Phe:1.8-2.2 |
1.0 2.9 5.0 4.0 1.0 2.0 2.0 4.0 1.0 2.0 1.0 1.0 2.0 2.0 |
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Water Content (K.F) |
≤8.0% |
6.5% |
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Acetonitrile |
NTM 410ppm |
15ppm |
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Sodium ion |
≤3.0% |
1.6% |
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Host Cell Protein |
≤0.01% |
Conforms |
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Host Cell DNA |
≤10.0ng/mg |
Conforms |
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Microbial Limits |
TAMC≤103cfu/g TYMC≤102cfu/g |
Conforms Conforms |
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Storage |
Storage in an air tight container, protected from light at a temperature of 2-8℃ |
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Conclusion |
The product tested Conform with In-house standard |
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Remark |
It ls only supplied as chemical product |
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🧩Application of Liraglutide CAS No.: 204656-20-2
1. Type 2 diabetes treatment：
Lowers blood glucose, boosts glucose-dependent insulin secretion, and reduces glucagon；suitable for adults and children ≥10 years；used alone or with metformin/sulfonylureas.
2. Weight management：
Reduces appetite and slows gastric emptying；for obese adults (BMI ≥30) or overweight adults (BMI ≥27) with weight-related complications；for obese adolescents ≥12 years (weight >60 kg)National Center for Biotechnology Information.
3. Cardiovascular risk reduction：
Cuts risk of heart attack, stroke, and cardiovascular death in adults with type 2 diabetes and heart disease.
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