Product based information:
Product Name: Isosorbide
Synonyms: Dianhydro-D-glucitol 98%;1,4:3,6-DIANHYDRO-D-SORBITOL;1,4:3,6-DIANHYDROGLUCITOL;1,4:
CAS: 652-67-5
MF: C6H10O4
MW: 146.14
EINECS: 211-492-3
Product Categories: Carbohydrates & Derivatives;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;11;Food Additivies;Inhibitors;652-67-5;1
Melting point 60-63 °C (lit.)
alpha 42 º (c=3, H2O)
Boiling point 175°C/2mmHg(lit.)
density 1.0945 (rough estimate)
vapor pressure 0.007Pa at 20℃
refractive index 45 ° (C=5, H2O)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka 13.17±0.40(Predicted)
Optical Rotation [α]20/D +45.2°, c = 3 in H2O
Water Solubility Soluble in alcohols, water and ketones.
Sensitive Hygroscopic
Appearance off-white to light yellow or beige crystals,
Specification
Purity: 98.5%
Supply Tons
Safety information:
Transport Information NON hazardous goods for shipment
HS Code 2932999099
Main Applications and Key Characteristics
| Application Field | Specific Uses | Key Characteristics & Notes |
|---|---|---|
| Pharmaceutical Field | Used as an active ingredient in diuretic drugs; used in the preparation of vasodilators for treating angina pectoris and heart failure; also used as a pharmaceutical excipient, or for lowering intraocular pressure to treat glaucoma. | Isosorbide itself is an osmotic diuretic, while its derivatives (e.g., nitrates) are important cardiovascular medications. |
| Polymer Materials | Serves as an important bio-based building block for synthesizing high-performance polymers such as polyesters, polycarbonates, and polyurethanes; used as a plasticizer in polymer production. | It is derived from glucose/sorbitol, making it an environmentally friendly green chemical. It imparts good heat resistance, optical transparency, and surface hardness to materials. |
| Research & Other | Used as a reference standard for scientific research, for example, in pharmacopoeia for the thin-layer chromatography identification of related excipients; used as an osmoprotectant or cryoprotectant to stabilize proteins and nucleic acids; in food contact materials, it can be used as a comonomer in polyester production, with a specific migration limit of 5 mg/kg. | High-purity products are suitable for analytical method development and quality control. |
Contact Person:
Crystal@coreychem.com
