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Hydroxypinacolone Retinoate (CAS: 893412-73-2)

October 17, 2025

Hydroxypinacolone Retinoate (CAS: 893412-73-2)

Hydroxypinacolone Retinoate, Abbreviated as HPR, is  a new type of retinoate derivative. Unlike other retinoic acid derivatives, HPR retains retinoic acid’s functional group and acts directly on its receptors without needing conversion, providing anti-aging effects similar to all-trans retinoic acid.

 

Basic information:

CAS NO

893412-73-2

Product Name

Hydroxypinacolone Retinoate(HPR)

INCI Name

Hydroxypinacolone Retinoate

Molecular formula

C26H38O3

Molecular weight

398.58

EINECS

412-073-2

Structure

Storage temp.

2-8℃

Catagory

Retinoids, Cosmetic Ingredients

Related products

Retinol (retinol, retinol), retinal, retinol palmitate, retinol propionate, Retinyl Retinoate

Primary Effects

Anti-Aging, Brightening & Spot Correction.

Stability

Light sensitive

Product Specifications

Appearance: Light yellow liquid (10% liquid form)

           Yellow powder(99% solid)

Product Manager E-mail

Grace Zhang

grace@coreychem.com

 

Product Introduction:

  • Liquid form: HPR 10% liquid

Content:

10% active ingredients

Active ingredient:

HPR (CAS No.: 893412-73-2)

Solvent:

Isosorbide dimethyl ether (CAS No.: 5306-85-4)

Appearance:

Light Yellow Liquid

Solvent (DMI) Function:

Safer and gentler for enhancing the penetration of active substances into the epidermis on the skin and around the eyes

Other content liquid also available, contact us for more details:

Grace Zhang  grace@coreychem.com 

  • Solid form : 99% purity powder

HPR 99% 1   HPR 99%

Functions:

HPR can be used for anti wrinkle products, whitening and spot removing products, anti-aging products Skin rejuvenation products Reduce melanin deposition and treat skin photoaging.

 

Formulation Recommendations:

  • Lotions, serums, creams, and anhydrous systems.

         Add to the oil phase of all emulsion formulations at a usage rate of 1-3% (as a 10% HPR solution).

         Recommended for use in nighttime products.

         Incorporate at low temperatures and combine with suitable humectants and anti-irritant agents.

  • Can be combined with other active ingredients and photostabilizers, making it suitable for use in daily-wear sunscreen products.
  • To enhance stability, incorporate stabilizing agents such as antioxidants and chelating agents. Additionally, maintain a neutral pH and use dark, airtight containers for packaging.

 

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