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Cholesterol (Plant origin)_CAS-No-57-88-5-News

August 14, 2025
***The basic characteristics and safety advantages
Cholesterol is an important component of the "lipid mixture" and is necessary for completing vaccination. Lipids are a general term for natural substances that are essentially insoluble in water. Together with mRNA fragments, they form so-called lipid nanoparticles (LNPs), which ultimately introduce vaccines into cells.
Plant source- cholesterol has dispelled concerns about the risk of animal borne viruses carried by animal derived cholesterol, expanded its use in the pharmaceutical, cosmetic, and health food industries, and can be used as high-end pharmaceutical excipients in non animal derived cell culture media for small molecule liposome drugs, nucleic acid drugs, mRNA vaccines, and protein based drugs.
 In addition, Plant derived cholesterol can also be used in mid to high-end cosmetics and in the preparation of vitamin D3 series products derived from plants.
√No animal-source risk: Avoid problems such as the perishability of animal raw materials, endogenous residues (such as prions) and exogenous contaminants (viruses, pesticides, etc.), as well as the risks of spongiform encephalopathy (TSE) and mad cow disease (BSE)
√Controllable composition: Non-genetically modified (Non-GMO), without animal gene residues, higher batch consistency, and reduced risk of unpredictable adverse reactions
√High purity and stability: Purity can reach over 99%, storage conditions are dry and protected from light (2-8°C or at room temperature, for injectable products, sealed and shaded), with a maximum validity period of up to 60 months

*** Applications of plant-source cholesterol
Plant-source cholesterol, due to its safety and functionality, is widely used in multiple fields such as medicine, cosmetics, and new materials:
1. Medicine
 Pharmaceutical excipients: As a high-end pharmaceutical excipient, used in the preparation of liposomes, fat emulsions, etc., for injection, for example, as a key component of mRNA vaccine lipid nanoparticles (LNP), stabilizing the bilayer structure and regulating lipid fluidity 4
 Synthetic raw materials: Used as the starting material for synthesizing vitamin D3, or as an intermediate for steroid drugs 
 Therapeutic application: Has anti-inflammatory and antioxidant effects, assisting in improving prostate health, reducing LDL cholesterol levels, and having potential therapeutic value for cardiovascular diseases, skin inflammation, etc.
2. Cosmetics
 As an active raw material, promoting skin metabolism, inhibiting inflammation, used in high-end skin care products (such as anti-aging, repair products)
3. Other fields such as advanced materials, application materials, etc.
Product manager: Joy Wu       Email: Joy@coreychem.com
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