| Product name | Fosfomycin phenethylamine |
| Synonym | phosphonomycin(r)-1-phenethylaminesalt; (r)-alpha-methylbenzenemethanamine(2r-cis)-(3-methyloxiranyl)phosphonate(1:1); (R)-(+)-Alpha-Phenylethylammonium,(1r,2s)-(-)-1,2-EpoxypropylPhosphonate; FOSFOMYCINPHENYLETHYLAMINE; ChemicalbookFosfomycinPhenethylamine-(+)-1-Phenylethylammonium(-)-Cis-1,2-Epoxypropylphosphonate; A-METHYLBENZENMETHAMINE(2R-CIS)-(3-METHYLOXYRANYL)-PHOSPHONATE; FosfoMycinCalciuMorSodiuMinterMediateproduct;FosfoMycinphenylethylaine |
| CAS NO. | 25383-07-7 |
| Appearance | White microcrystalline powder |
| Purity | 98.0% -102.0% |
| MF | C11H18NO4P |
| MW | 259.24 |
| Related categories | Pharmaceutical intermediates |
| Structural formula |  |
| Product Manager Email | sophia@coreychem.com |
Fosfomycin phenethylamine (fosfomycin) is a combination antibacterial drug consisting of fosfomycin, levofloxacin, metronidazole, and other ingredients. It is primarily used to treat infections caused by susceptible bacteria, such as urinary tract infections, respiratory tract infections, and skin and soft tissue infections. It exerts a broad-spectrum antibacterial effect by inhibiting bacterial cell wall synthesis and interfering with DNA replication.
1. Nature:
It is a salt formed by combining the antibiotic fosfomycin with phenylethylamine. This salt form improves the physicochemical properties of fosfomycin, making it more suitable for pharmaceutical formulation.
Main Use: A broad-spectrum injectable antibiotic.
2. Key Features and Advantages
Good Water Solubility: Fosfomycin phenylethylamine salt has high solubility in water, making it well-suited for injection.
High Bioavailability: Through intramuscular or intravenous injection, the drug is almost completely absorbed by the body, rapidly reaching effective blood concentrations.
Broad Antimicrobial Spectrum: It exhibits excellent inhibitory activity against a wide range of Gram-positive and Gram-negative bacteria.
Unique Mechanism of Action: Fosfomycin kills bacteria by inhibiting the early stages of bacterial cell wall synthesis (by inhibiting pyruvate UDP-N-acetylglucosamine transferase). This unique mechanism makes it less likely to develop cross-resistance with other common antibiotics, such as β-lactams and macrolides.
Fosfomycin phenethylamine salt (commonly known as fosfomycin phenethylamine salt) is an important injectable formulation of fosfomycin. Leveraging fosfomycin’s unique antibacterial mechanism, it offers an effective option for the clinical treatment of a variety of bacterial infections, particularly for severe infections where oral administration is unsuitable or where rapid onset of action is required.
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Contact Information:
Contact: Sophia Li
Email: sophia@coreychem.com
