Esculin (CAS 531-75-9): Synthesis and Application of Fluorinated Horner Reagent with Full Analysis
1、 Product Overview
Esculin is a naturally occurring coumarin glycoside, also known as Esculetin-6-O-glucoside.
Its key value comes from its characteristic coumarin glycoside structure, natural-product origin, and suitability for phytochemical, biochemical, analytical, and pharmaceutical research.
2、 Basic Product Information
Product Name: Esculin
Synonyms:
Esculetin-6-O-glucoside; Esculin
CAS NO.: 531-75-9
Molecular Formula: C₁₅H₁₆O₉
Structural formula：
Molecular Weight: Approximately 340.28 g/mol
Appearance: White powder
Odor: Essentially odorless
Water Solubility: Soluble in water
Main Function: Natural product research compound / analytical reference material
Product Form: Fine crystalline powder
Typical Application: Phytochemical research, natural product analysis, biochemical research, analytical testing, and pharmaceutical research
Product Manager: Cherry Zhu
Email: Cherry@coreychem.com
3、 Frequently Asked Questions (FAQ)
1) What is Esculin and what are its key characteristics?
Esculin is a naturally occurring coumarin glycoside and is also known as Esculetin-6-O-glucoside.
Its key characteristics include a coumarin-based structure, glycoside functionality, and suitability for natural product and biochemical research.
It is commonly supplied as a crystalline powder and can be used as a research compound or analytical reference material.
2) What are the key physical and chemical properties of Esculin, and what should be considered during operation?
Esculin is generally supplied as a white to pale yellow crystalline powder with good water solubility.
During handling, contamination and unnecessary exposure to moisture, heat, and direct light should be avoided. Appropriate laboratory practices, ventilation, gloves, and eye protection should be used when handling the product.
Users should always refer to the latest SDS for detailed handling, storage, and safety information.
3) What fields can Esculin be applied to?
Esculin is mainly used in natural product and biochemical research. Its major application fields include:
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Phytochemical research
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Natural product research
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Plant extract analysis
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Analytical chemistry
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Biochemical research
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Pharmaceutical research
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Bioactive compound research
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Research involving coumarin glycosides
Its main value is as a defined coumarin glycoside that can support compound identification, characterization, and comparative research.
4) What special precautions should be taken during transportation, and how should Esculin be handled after leakage or contact?
During transportation, Esculin should be kept in tightly sealed, compatible packaging and protected from moisture, contamination, direct light, and physical damage.
Because the product is supplied as a fine powder, unnecessary dust generation should be avoided during handling. In the event of a spill, collect the material using appropriate methods while minimizing dust formation.
If the material contacts the skin or eyes, rinse thoroughly with clean water. Detailed first-aid and spill-response procedures should follow the SDS for the specific product grade.
5) What materials or research systems can Esculin be used with?
Esculin is primarily used as a research compound and analytical reference material rather than as a reactive industrial building block.
It can be used in studies involving plant extracts, natural products, coumarin derivatives, biochemical systems, and analytical samples.
Its application and concentration should be selected according to the specific research objective, analytical method, and experimental requirements.
4、 Application Cases
1) Natural Product Research – Coumarin Glycoside Research
Esculin is an important research compound for studies of naturally occurring coumarin glycosides.
It can be used to investigate the chemical composition, structural characteristics, and distribution of coumarin-related compounds in plant-derived materials.
2) Phytochemical Research – Plant Extract Analysis
Esculin can be used as a reference compound for the analysis of botanical extracts and plant-derived samples.
Its defined chemical structure makes it useful for compound identification and comparison during chromatographic and spectroscopic studies.
3) Analytical Chemistry – Reference Standard
Esculin can serve as an analytical reference material in qualitative and quantitative research.
It is particularly useful in chromatographic analysis, including HPLC-based methods, for the detection and determination of Esculin in research samples.
4) Biochemical Research – Bioactive Compound Studies
Esculin can be used in biochemical research investigating naturally occurring bioactive compounds and coumarin-related molecules.
It provides a defined compound for laboratory studies involving compound characterization, biological evaluation, and comparative analysis.
5) Pharmaceutical Research – Natural Product-Based Research
Esculin can serve as a research compound in pharmaceutical and bioactive-molecule studies.
It can support research involving natural-product-derived compounds, molecular characterization, biological evaluation, and structure-activity-related investigations.
6) Quality Control and Botanical Ingredient Analysis
Esculin can be used as a reference compound in the quality evaluation of selected botanical materials and plant-derived ingredients.
Analytical testing can help support the identification, consistency assessment, and characterization of samples containing Esculin or related compounds.
5、 Safety and Storage
Store Esculin in a cool, dry, and well-ventilated area and keep the original container tightly sealed.
Protect the product from excessive moisture, direct light, heat, contamination, and unfavorable storage conditions.
Because Esculin is supplied as a powder, avoid unnecessary generation and inhalation of dust during handling. Appropriate ventilation and personal protective equipment should be used during weighing, transfer, and laboratory operations.
6、Product Manager Information
Product Manager: Cherry Zhu
Email: Cherry@coreychem.com
