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Diphenyl Sulfone CAS 127‑63‑9 | High‑Temperature Solvent for High‑Performance Polymer Manufacturing

September 24, 2026

Product main description

Diphenyl sulfone, also known as DPS or phenyl sulfone, is an organosulfur crystalline compound widely applied in fine‑chemical and polymer industries. It features outstanding thermal stability and chemical inertness, maintaining stable performance under continuous high‑temperature reaction conditions. It is well‑known as an ideal high‑boiling‑point reaction medium for polycondensation of high‑performance engineering plastics. Besides polymer manufacturing, it also serves as key intermediate for pharmaceutical and agro‑chemical synthesis, as well as functional additive for thermal‑paper and special coating systems.

Technical information

  1. Appearance: White crystalline powder or crystal
  2. Solubility: Insoluble in cold water, slightly soluble in hot water; soluble in hot ethanol, ether, benzene and other organic solvents
  3. Melting Point: 123‑129 °C
  4. Boiling Point: 379 °C at 760 mmHg
  5. Density: ~1.25 g/cm³
  6. Refractive Index: n20D 1.594
  7. Purity: ≥99%
  8. Structure:        diphenyl sulfone cas 127 63 9 structure   

Frequently Asked Questions (FAQ)

1)What are the core advantages of Diphenyl Sulfone as a high‑temperature reaction solvent?
–Excellent thermal stability — It hardly decomposes under long‑time high‑temperature conditions, and can adapt to the high‑temperature polycondensation environment for PEEK, PES and PSU production, avoiding solvent decomposition or volatilization risks of ordinary organic solvents. –Chemical inertness — It does not participate in polymerization reactions, will not introduce impurity groups, and helps to obtain high‑molecular‑weight polymer products with stable quality. –Recoverable performance — It can be separated, purified and recycled after reaction, effectively reducing comprehensive production costs for downstream manufacturers. –Wide compatibility — It has good solubility for various reaction raw materials and can match multiple high‑temperature synthesis processes.

2)What are the mainstream synthesis methods for Diphenyl Sulfone?
Route 1: Oxidation of diphenyl sulfide Diphenyl sulfide is oxidized with hydrogen peroxide or other oxidants under controlled conditions to obtain diphenyl sulfone. This route has high product purity and is widely adopted in fine‑chemical factories. Route 2: Sulfonation and condensation process Benzene undergoes sulfonation and subsequent condensation reaction under catalyst conditions to generate diphenyl sulfone. This process is more suitable for large‑scale bulk industrial production.

3)How does Diphenyl Sulfone compare with other high‑temperature solvents such as DMSO in polymer synthesis?
Diphenyl sulfone has much higher thermal‑decomposition temperature than DMSO and other sulfoxide solvents. DMSO will decompose and produce by‑products at relatively high temperature, while diphenyl sulfone can keep stable above 300℃. Although DMSO is cheap, it cannot meet the temperature requirement of PEEK polycondensation. Diphenyl sulfone is the preferred medium for high‑end engineering‑plastic production, despite its higher unit price.

4)Why is melting‑point range and impurity content the key inspection indicators for Diphenyl Sulfone purchasing?
In high‑temperature polymer synthesis, impurity residues will interfere polycondensation reaction and reduce polymer molecular weight. Melting‑point deviation can directly reflect product purity. For electronic‑grade polymer production, heavy‑metal residue must be strictly controlled; for thermal‑paper industry, crystal particle size also influences end‑product coating effect. Buyers need to confirm index requirements according to their own downstream scenarios.

5)What safety risks should operators pay attention to during daily handling?
Diphenyl sulfone is not classified as dangerous goods for transportation, but its dust may cause mild irritation to skin, eyes and respiratory tract. Avoid dust inhalation during operation; wear protective gloves and goggles. In case of contact, flush with plenty of clean water timely. Keep away from strong oxidizing agents during storage and transportation.

Application Cases

1)How does Diphenyl Sulfone work in manufacturing high‑performance engineering plastics such as PEEK, PES and PSU?
Diphenyl sulfone acts as high‑boiling inert solvent for polycondensation reaction. Under high‑temperature conditions, it dissolves reaction monomers and provides stable liquid‑phase reaction environment. It will not take part in polymer chain growth. After polymerization, diphenyl sulfone can be separated and recovered. This process is critical for producing high‑strength, heat‑resistant engineering‑plastic particles widely used in aerospace, medical implant and precision‑equipment fields.

2)What role does Diphenyl Sulfone play in thermal‑sensitive coating for thermal paper?
It serves as thermal sensitizer inside thermal‑paper coating formula. It optimizes melting performance of the coating system, accelerates color‑developing speed during heating, improves handwriting clarity and prolongs printed content storage life. It is one of important auxiliary raw materials for commercial thermal‑paper production.

3)In what way is Diphenyl Sulfone applied in pharmaceutical intermediate synthesis?
Diphenyl sulfone skeleton is introduced into multiple sulfone‑series drug‑molecule structures. It works as high‑temperature reaction medium for high‑temperature cyclization and rearrangement steps in API intermediate preparation. Its stable property guarantees reaction repeatability for lab‑scale R&D and pilot‑plant production.

4)What value does Diphenyl Sulfone bring to agro‑chemical synthesis?
It can be used as auxiliary raw material for acaricide and pesticide synthesis. The sulfone structure helps improve target molecule stability under complex field environment. It is adopted in several research and production projects of new‑generation agro‑chemical products.

5)How is Diphenyl Sulfone used for modification of special high‑temperature‑resistant coatings?
As functional additive for anti‑corrosion and heat‑resistant coating, diphenyl sulfone improves high‑temperature tolerance and anti‑aging performance of coating layers. The modified coating can be applied for electronic‑component surface protection and some industrial high‑temperature equipment anti‑corrosion scenarios.

Packaging

–For Laboratory / Research Scale: · Primary Container: Sealed glass bottle, protect from dust contamination. · Atmosphere: Keep tightly sealed under normal room environment.

–For Bulk / Industrial Scale: · Standard Packaging: Supplied in 1 kg, 5 kg, 10 kg or 25 kg fiber drums / paper drums with inner PE liner. · Custom Packaging: Customized packing solution can be offered according to customer’s special handling and storage requirements.

Storage

· Temperature: Store under cool and dry room‑temperature environment (15‑25℃). Avoid long‑time exposure under high‑temperature surroundings. · Atmosphere: Keep container tightly closed to prevent dust and moisture from entering. · Light Protection: Ordinary warehouse storage is acceptable; avoid long‑term strong direct sunlight. · Container: Store in cool, dry and well‑ventilated warehouse area. Keep far away from strong oxidizing agents. Do not mix‑store with food and feed raw materials. Under proper sealed storage, shelf life reaches 24 months.

Product Manager Information

Product Manager: Amber Yin Email: amber@coreychem.com

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