Custom Synthesis
Career Henan Chemical Co. focuses on providing one-stop service from molecular design to commercialization for global customers, and our core competencies include:
R&D and custom synthesis of drug molecular building blocks:
process development and optimization:
High-end amino acid, peptide and antibody product development:
Customized synthesis under GLP and GMP environment:
Integrated “CRO + CDMO” services:
Coreychem Custom Synthesis Overall Process
- The customer provides the target compound structure, purity specifications, quantity requirements and lead time.
- Our project manager and R&D team review the technical difficulties and assess the feasibility of the route, cost and compliance requirements.
- Signing of confidentiality agreement (CDA/NDA) according to customer’s requirements to ensure the security of customer’s intellectual property and material information.
- Chemists design multiple synthetic routes or improve on existing literature methods, optimizing processes based on green chemistry principles.
- Retrieve required reagents, solvents, catalysts and perform economic evaluation and supply chain lead time planning.
- Pilot scale-up programs, such as kilogram or larger batches, are developed to support subsequent batch production.
- Conduct small scale synthesis experiments in the laboratory to validate the feasibility of the synthetic route.
- Reaction conditions (temperature, solvent, concentration), yields and purification methods are continuously optimized based on batch feedback.
- After successful small pilot, we enter into pilot or small batch GMP production (kilogram to ten kilogram grade).
- GMP production is carried out under our GMP grade workshop and equipment to ensure that CMC specifications are met.
- Production Records→Critical Parameter Confirmation→ QC Data → COA.
- Package and ship compounds (e.g., solid powders, solutions, or lyophilized powders) according to customer requirements.
- Provide continuous process support, such as subsequent batch adjustment, process improvement or technology transfer.
- Maintain a high level of responsiveness and communicate with customers on a regular basis for feedback to ensure smooth project progress.
Our Ethics
We adhere to the core values of “scientific rigor, customer first, honesty and law-abiding, green and sustainable”:
Compliance
Strictly comply with GLP/GMP quality standards and international pharmaceutical regulatory requirements to ensure product quality and data integrity.
Customer Commitment
Respect the intellectual property rights of customers, guarantee the confidentiality of information, and establish independent access and tracking systems for all projects.
Environmental protection and sustainability
We are committed to the development of green chemistry routes, reducing waste emissions and continuously optimizing production processes.
Employee and Social Responsibility
The company has established a perfect career development channel and safety management system, and actively participates in social welfare programs to fulfill its corporate social responsibility.
