Product Name:Ascomycin
CAS: 104987-12-4
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Appearance |
White to off-white to yellowish solid |
Off-white solid |
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Identification |
HPLC:Retention time of major peak in the chromatogram obtained from test solution corresponding to that obtained with reference solution |
Conforms |
|
IR： |
IR：Spectrum of test sample should confirm to that reference standard spectrum |
|
|
Related Substances |
Impurity FK523≤0.5% |
0.25% |
|
Related Substances |
Individual unspecified impurity(deduct tautomer)≤0.1% |
0.07% |
|
Related Substances |
Total impurities(deduct tautomer) ≤1.0% |
0.52% |
|
Water |
≤1.0% |
0.36% |
|
Assay (on anhydrous basis,sum of ascomycin and tautomer II) |
96%~102.0% |
99.5% |
Pharmaceutical R&D Immunosuppression A potent immunosuppressant. It inhibits T-cell activation and the production of key cytokines like Interleukin-2. It is widely used in scientific research to prolong the survival of transplanted organs and as a tool molecule for studying the immune system.
Dermatological Treatment Its analogues (e.g., Pimecrolimus) have been developed for treating inflammatory skin conditions like atopic dermatitis (eczema).
Anti-cancer Research Studies have shown that Ascomycin and its analogue Tacrolimus can inhibit the growth, migration, and invasion of certain cancer cells, such as melanoma.
Agricultural Application Fungicide As an agricultural antibiotic, it can effectively control various fungal diseases in crops, such as tomato gray mold, cucumber gray mold, and southern corn leaf blight.
judy@coreychem.com
