📋Basic information:
- Chemical name: Alpha Lipoic Acid
- CAS No.: 1077-28-7
- Molecular Formula: C8H14O2S2
- Molecular Weight: 206.33
Product Mananger: grace@coreychem.com
📌Specification:
| Items | Specifications | Results |
|---|---|---|
| Appearance | Slightly yellow crystal powder | Conforms |
| Identification | IR-Spectroscopy | Conforms |
| Melting Point | 60.0~62.0℃ | 61.8℃ |
| Specific rotation | -1.0° to +1.0° | 0° |
| Loss on drying | 0.2% max | 0.08% |
| Residue on Ignition | 0.1% max | 0.02% |
| Heavy Metals | 10ppm max | Conforms |
| Lead | 3ppm max | <3ppm |
| Arsenic | 1ppm max | <1ppm |
| Cadmium | 0.1ppm max | <0.1ppm |
| Mercury | — | — |
| Chromatographic purity | ||
| Individual Impurities | 0.1% max | 0.02% |
| Total Impurities | 2.0% max | 0.07% |
| Chromatographic purity (TLC) | Conforms | Conforms |
| Residual Solvents | ||
| Cyclohexane | 3880ppm max | 480ppm |
| Ethyl Acetate | 500ppm max | 40ppm |
| Toluene | 20ppm max | 10ppm |
| Microbiology | ||
| Total aerobes counts | 1000 cfu/g max | <10 cfu/g |
| Moulds and Yeasts | 100 cfu/g max | <10 cfu/g |
| E.coli | Absence/g | Not Detectable |
| Staphylococcus aureus | Absence/g | Not Detectable |
| Salmonella | Absence/g | Not Detectable |
| Particle Size | 100% through 40 mesh | Conforms |
| Loose Bulk Density | — | 0.40g/ml |
| Assay (dried basis) | 99.0%~101.0% | — |
🧩Application of Alpha Lipoic Acid CAS No.: 1077-28-7
1. Pharmaceutical Intermediate
Used for synthesizing APIs including R-alpha lipoic acid, lipoate salts and lipoamide; also applied as intermediates for anti-tumor, liver-protective, hypoglycemic and neuroprotective drugs. In new drug development, it is a key raw material for medicines against liver injury, neurodegenerative disorders (Alzheimer’s disease) and auxiliary lipid-lowering agents.
2. Raw Material for Dietary Supplements
- Hypoglycemic supplements: improves insulin sensitivity and stabilizes postprandial blood glucose, a core ingredient in blood sugar-controlling dietary supplements;
- Anti-aging & liver protection: eliminates free radicals, delays bodily oxidative aging and promotes liver detoxification;
- Fat loss & metabolism boosting: accelerates mitochondrial energy metabolism and facilitates fat breakdown, widely used in weight-loss powder and capsule formulations.
Available dosage forms: hard capsules, softgels, powders, effervescent tablets and functional drinks; it is a top-selling raw material for health products across Europe and America.
3. Cosmetic & Skincare Raw Material
Added into premium anti-aging serums, creams and stock solutions. It penetrates the epidermis to scavenge free radicals, prevents photoaging, reduces fine lines and repairs oxidatively damaged skin; it also inhibits glycation-induced dullness, commonly formulated into early anti-aging and repairing cosmeceutical products.
Contact us (grace@coreychem.com) now for more details!
