Product Name: Adefovir
CAS:106941-25-7
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Appearance |
Light or slight white powder |
White powder |
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Identification (UV) |
Maximum absorption at 261nm |
Conforms |
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Loss on drying |
≤1% |
0.08% |
Although effective, the core status of Adefovir Dipivoxil in clinical practice has changed due to its relatively high rate of drug resistance and potential nephrotoxicity:
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Current Status: In the treatment of chronic hepatitis B, Adefovir Dipivoxil has largely been replaced by drugs such as Tenofovir (e.g., TDF, TAF), which offer higher efficacy and better safety profiles.
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Use in Specific Situations: Adefovir remained effective against viral strains that were resistant to Lamivudine (an earlier anti-HBV drug), making it a past option for “rescue therapy” following the development of resistance.
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judy@coreychem.com
