English

6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE (CAS 885693-20-9)

July 15, 2026

Contact Manager: Emma Song    Email Address: emma@coreychem.com

Product Overview

6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE is a protected cyclic boronate ester intermediate. Equipped with Boc amino protecting group and pinacol boronate, it features excellent solubility, air stability and high reactivity for Suzuki-Miyaura coupling, widely adopted in pharmaceutical heterocycle synthesis. We supply research & industrial grade batches with consistent quality for global labs and manufacturers.

Core Specifications

  • CAS No.: 885693-20-9
  • Molecular Formula: C₁₆H₂₈BNO₄
  • Molecular Weight: 309.21
  • Appearance: White/off-white crystalline solid
  • Purity: ≥98% (NMR/HPLC tested)
  • Key Structure: N-Boc protected tetrahydropyridine ring + pinacol boronate
  • Storage: Sealed, cool & dry place, avoid moisture

Product Advantages

  1. Stable pinacol boronate structure, less hydrolysis than free boronic acid
  2. Removable Boc group enables selective amine modification in multi-step synthesis
  3. Low heavy metal impurities, ideal for drug candidate development
  4. Uniform batch indicators, complete COA, NMR and SDS provided
  5. Flexible packaging: 1g–25kg, custom synthesis available

Main Applications

  1. Medicinal Chemistry Intermediates Core building block for kinase inhibitors, CNS drugs, anti-tumor and anti-viral heterocyclic molecules. The dihydropyridine scaffold constructs complex nitrogen-containing drug skeletons.
  2. Organic Cross-Coupling Synthesis Standard substrate for Suzuki coupling to assemble biaryl and fused heterocyclic fine chemicals.
  3. Compound Library & Lab Research Widely used in hit screening, new synthetic methodology and small molecule library construction.

Packaging & Safety

Packed with moisture-proof aluminum foil bags/drums. Standard PPE required during handling. Full shipping documents support worldwide delivery.

Our Service

Professional boronate ester manufacturer with stable stock, fast lead time and dedicated technical support. Welcome sample testing and bulk order inquiries.

You can also fill out our online message form and we will contact you within 24 hours.