4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid (CAS 137281-39-1): Product Profile, Parameter and Industrial Application Analysis
1. Product Overview
4-Cyanopyrazole (1H-pyrazole-4-carbonitrile) is a valuable pyrazole heterocyclic building block, which is widely used in organic synthesis and pharmaceutical & agrochemical R&D.
With cyano group at the 4-position of pyrazole ring, this compound provides versatile reactive sites for hydrolysis, reduction and cyclization reactions. It serves exclusively for laboratory research and intermediate synthesis rather than finished API or pesticide, and occupies an important position for constructing pyrazole-containing bioactive molecules.
2、 Basic Product Information
1）Product Name: 4-CYANOPYRAZOLE
2）CAS NO.：31108-57-3
3）Molecular formula: C4H3N3
2）CAS NO.：31108-57-3
3）Molecular formula: C4H3N3
5）Structural formula:
6）Purity: ≥ 98%
7）Appearance: White to off-white crystailline powder
8）Product Manager Email:Cara@coreychem
7）Appearance: White to off-white crystailline powder
8）Product Manager Email:Cara@coreychem
3、 Frequently Asked Questions (FAQ)
1. Q: What functional groups are present in 4-Cyanopyrazole?
A: It contains a pyrazole heterocycle and a cyano group (-CN) at the 4-position, which can undergo hydrolysis, reduction and cyclization reactions.
2. Q: What is the typical purity grade available for this product?
A: Standard grade ≥98% (HPLC).
3. Q: What category of chemical does it belong to for export declaration?
A: It falls under pyrazole derivatives, classified as fine chemical R&D intermediate, not finished drug or pesticide.
4. Q: What hazards should be noted during lab handling?
A: It may cause irritation to skin, eyes and respiratory tract; dust inhalation should be avoided.
5. Q: What main chemical reactions can this molecule participate in?
A: Alkylation, Michael addition, cyclization, cyano hydrolysis and reduction to generate various pyrazole derivatives.
4、 Application Cases
1. Core pharmaceutical Intermediate:
Its mainy used to construct pyrazole pharmacophores for APOL1 inhibitors, S1P1 receptor modulators, kinase inhibitors, GPCR modulators and anti-inflammatory / anti-tumor lead compounds.
2. Agrochemical Synthetic Intermediate:
It can be applied for synthesis of pyrazole fungicides, insecticidal and acaricidal active agrochemical molecules.
3. Organic Synthesis & Catalysis Building Block:
The pyrazole nitrogen and 4-cyano group support alkylation, Michael addition and cyclization; can act as ligand for catalytic reaction research.
4. Fine Chemical Intermediate:
It is also used for manufacturing dyes and functional nitrogen-containing heterocyclic polymers.
5. Laboratory Research Reagent:
It can serve as reference standard and raw material for pharmacological and molecular biology laboratory R&D.
5、 Safety and Storage
1）Store in a cool, well ventilated area and keep the container sealed；
2）Sensitive to moisture, avoid prolonged exposure to humid air to prevent quality change；
3）Store away from light, room temperature storage is acceptable, avoid high temperature；
4）Store separately from strong oxidants.
6、Product Manager Information
Product Manager: Cara Lee
Email: cara@coreychem.com
