4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-indazol-3-amine
CAS No.: 2189684-53-3
Molecular Formula: C₁₄H₁₅F₃N₂O₂S₂
Molecular Weight: 364.41 g/mol
Synthesis is stable and reproducible, and impurity profiles have been verified, facilitating seamless large-scale production and serving as a key guarantee of high quality.
💊 Core Pharmaceutical Uses
The most crucial and clearly defined use of this compound is as a key pharmaceutical intermediate for lenapavir.
Lenacapavir is an innovative anti-HIV drug, belonging to the capsid inhibitor class. Its mechanism of action is to inhibit HIV replication by interfering with the assembly and function of the viral capsid.
In the synthesis of complex molecules like lenapavir, the pinacol ester borate in this compound’s structure is a very important functional group. It can connect complex molecular fragments through a highly efficient Suzuki coupling reaction, thereby constructing the core structure of lenapavir.
Therefore, this compound is an indispensable basic building block for the synthesis of this cutting-edge drug.
💊Supply Advantage
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