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2,5-Tetrahydrofurandimethanol CAS No.: 104-80-3

January 20, 2026

2,5-Tetrahydrofurandimethanol CAS No.: 104-80-3, or 2,5-bis(hydroxymethyl)tetrahydrofuran (THFDM), is a multifunctional and renewable furan-based compound. It functions as an environmentally friendly, low-toxicity, and biodegradable solvent, and also acts as a key precursor for producing high-performance diesel/gasoline additives and bio-based film-forming aids.

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Basic information:

  • Chemical name: 2,5-Tetrahydrofurandimethanol
  • Other Name: THFDM
  • CAS: 104-80-3
  • Molecular Formula: C6H12O3
  • Molecular Weight: 132.16

 

Specification:

Appearance: Colorless liquid

Purity: 99%min

Melting Point: ˂-70°C

Boiling Point: 230±5°C

Relative Density: 1.130g/cm³ at 25 °C

Stability: Stable at room temperature

Storage:Keep sealed, stored in a cool, dry place

Main Applications of 2,5-Bis(hydroxymethyl)tetrahydrofuran

I. Chemical Synthesis Field

  1. Acts as a key monomer for polymer synthesis, makes high-performance polyesters and polyurethanes, and improves the mechanical properties and weather resistance of materials.
  2. Relies on its multi-functional group properties, and is widely used to synthesize high-value chemicals such as polymers and pharmaceutical intermediates.
  3. Applies to the synthesis of polyether polyols, produces low-volatility and high-activity polyethers for polyurethane foams, elastomers and other products.
  4. Serves as a low-toxic, biodegradable green solvent for various organic synthesis and chemical reactions.

II. Materials, Coatings & Adhesives Field

  1. Works as a resin modifier, enhances the adhesion, flexibility and water resistance of epoxy resins and phenolic resins, and is suitable for coatings and adhesives scenarios.
  2. Acts as a crosslinking agent and raw material for adhesives and coatings, produces water-resistant and chemical-resistant special coatings as well as eco-friendly adhesives (e.g., wood adhesives, industrial structural adhesives).
  3. Serves as a key raw material for manufacturing bio-based coatings, resins and film-forming additives.

III. Environmental Protection & Biodegradable Field

  1. Produces biodegradable materials (e.g., degradable polyesters, polyethers), which are applied in environmental protection fields such as disposable packaging and biomedical consumables.
  2. Acts as a green raw material for fine chemicals, synthesizes various surfactants for emulsification, dispersion and wetting processes in daily chemical, textile, printing and dyeing industries.

IV. New Energy Field

  1. Can be used as a potential liquid hydrogen storage material in fuel cells, providing a technical path for new energy development.
  2. Serves as a precursor for high-performance diesel or gasoline additives, improves fuel combustion efficiency and reduces pollution.

V. Pharmaceutical & Pesticide Field

  1. Synthesizes pharmaceutical and pesticide intermediates, and provides core raw materials for the production of antibacterial, anti-inflammatory drugs and high-efficiency, low-toxicity pesticides.

VI. Daily Chemical & Textile Field

  1. Modifies textile finishing agents, improves the wrinkle resistance, softness and wash fastness of textiles, and is suitable for the post-finishing of cotton, linen, chemical fiber and other fabrics.

 

 

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