2,5-Furandimethanol CAS No.: 1883-75-6

February 28, 2026

2,5‑Furandimethanol (also called FDM) is a key bio‑based diol. As a furan-based bio-based diol, FDM exhibits excellent rigidity and thermal stability, making it widely applicable in the synthesis of high-performance polyesters and polyurethanes. It can be used in various fields such as coatings, resins, and plasticizers, demonstrating the potential to replace traditional petroleum-based polyols. FDM is an indispensable basic monomer for the development of green materials.

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Basic information:

Chemical name: 2,5-Furandimethanol
Other Name: furan-2,5-diyldimethanol (FDM）
CAS: 1883-75-6
Molecular Formula: C6H8O3
Molecular Weight: 128.13

Specification:

Appearance:	White to light yellow powder
Purity:	99%min
Melting Point:	74-77℃
Flash Point	120℃
Boiling Point	275℃
Relative Density:	1.283
Storage：	Stored at 2-8℃. Keep sealed, stored in a cool, dry and dark place

Application of 2,5-Furandimethanol (FDM) CAS:1883-75-6

🧪 Key Applications

2,5-Furandimethanol has a wide range of applications, primarily in polymer science, biofuel research, and biomedical studies:

Field	Specific Applications & Characteristics
Polymer Synthesis	Serves as a key monomer for high-performance polymers. It is used to manufacture polyesters (including biodegradable types) and polyurethanes, acting as a sustainable alternative to petrochemical polyols in coatings, resins, and plasticizers. It is also a precursor for epoxy resins.
Biofuels	Acts as a biofuel additive; its etherification products can improve the energy density and blending properties of biodiesel. It is also a potential precursor for liquid alkanes (drop-in fuels).
Biomedical Research	Used as an intermediate for pharmaceutical synthesis. Studies indicate it is a metabolite of the medicinal fungus Phellinus and is used in fungal infection research and anti-leukemia studies. Additionally, it functions as an artificial receptor in molecular recognition research.
Other Research	Employed as a model compound in photocatalytic and electrochemical studies. It is a crucial intermediate in the production of 2,5-Furandicarboxylic acid (FDCA)—a vital bio-based plastic monomer seen as a replacement for petroleum-derived terephthalic acid—via oxidation.

🔬 Research Progress & Biological Activity

Catalytic Synthesis: It is primarily produced via the selective hydrogenation of 5-Hydroxymethylfurfural (HMF). Current research focuses on developing efficient catalysts (e.g., cobalt-based, copper-based) and biocatalytic methods (e.g., using engineered E. coli whole-cell catalysts) to achieve high yields (often exceeding 95%) and enable green production.
Biological Activity: Beyond its role as a synthetic building block, the compound itself exhibits potential biological activities, including inhibitory effects against certain Gram-positive and Gram-negative bacteria.