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2,5-Dihydroxybenzoic acid CAS: 490-79-9

August 25, 2026

Product Overview

2,5-Dihydroxybenzoic acid is an active metabolite of salicylic acid with a broad spectrum of biological activities, including anti-inflammatory, antirheumatic, and antioxidant properties. It naturally occurs in plants and has demonstrated significant biological activity, making it a promising candidate for topical applications in the cosmetic and pharmaceutical industries 

Synonyms: Gentisic acid, 2,5-DHBA, Hydroquinonecarboxylic acid, 5-Hydroxysalicylic acid

Product Mananger: grace@coreychem.com

Specifications

Item Specification
CAS No. 490-79-9
EINECS No. 207-718-5
Molecular Formula C₇H₆O₄
Molecular Weight 154.12
Appearance White to light beige crystalline powder
Purity ≥ 98%, ≥ 99%  
Loss on Drying ≤ 0.5%
Packaging 100g/Bag, 1KG/Bag or as per request
Storage Keep in a cool, dry, well-ventilated place; store in tightly closed container under inert atmosphere (N₂) at room temperature; protect from light and moisture
Transport Non-dangerous goods (non-DG); not listed in China’s Catalog of Hazardous Chemicals; standard export declaration applies
 

Applications

1. Pharmaceutical and Medical Applications  

  • Used as an important pharmaceutical intermediate for synthesizing various drugs, including those with antipyretic and analgesic properties.
  • Functions as an antioxidant excipient in pharmaceutical formulations to enhance drug stability.
  • Available in pharmaceutical grade for use as a medicinal excipient.
  • Shows potential as an active ingredient for topical applications, with demonstrated efficacy against microorganisms including Staphylococcus aureus, Escherichia coli, and Cutibacterium acnes, along with low cytotoxicity profiles 

2. MALDI‑TOF Mass Spectrometry

A classic matrix for MALDI‑MS. Widely used for laser desorption‑ionization analysis of peptides, proteins, polysaccharides, glycolipids and polymers. Especially suitable for neutral polysaccharide analysis, mainly generating sodium adduct ions [M+Na]⁺. Research‑grade product requires ≥99% HPLC purity with low metal‑ion impurities.

3. Industrial Intermediates

  • Building block for resins, polyesters, and plasticizers
  • Intermediate for dyestuffs, preservatives, and rubber chemicals
  • Thermal paper color developer: An emerging application — used as a color-forming agent in thermal-sensitive coatings

4. Food & Cosmetics

  • Food antioxidant additive: Prevents oxidation of oils and vitamins, extends shelf life
  • Cosmetic antioxidant / preservative: Extends product shelf life with additional whitening and anti-aging properties

Our Advantages

✔ Mass production, stable quality, long‑term order support
✔ fast delivery for samples & bulk goods
✔ Full documents: COA, English‑version MSDS for customs clearance
✔ Flexible packing for lab test and industrial production
 
For quotation and sample request, please contact: grace@coreychem.com.
 
 

 

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