Product name	2,3-Butanediol, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethyl-
CAS NO.	335327-93-0
Appearance	White solid
Purity	99% Min
MF	C22H30O6
MW	390.47
Structural formula
Related categories	Custom-synthesized product
Product Manager Email	sophia@coreychem.com

Product Applications of  2,3-Butanediol, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethyl-

I. Key Intermediates for Pharmaceutical Synthesis

Raw Material for Construction of Anticancer Drug Scaffolds

The core 2,3-butanediol scaffold of this molecule serves as a vital intermediate for synthesizing antitumor agents including podophyllotoxin, etoposide and teniposide. This product is obtained via reduction of dibenzylbutyrolactone, followed by cyclization to construct the aryltetralin lignan parent skeleton, supporting the total synthesis of anticancer active pharmaceutical ingredients (APIs).

Chiral Building Blocks for Asymmetric Synthesis of Diverse Lignans

Two chiral centers exist at the C2 and C3 diol positions of the molecule. It can be applied to the asymmetric synthesis of optically active lignans to produce naturally occurring chiral lignan monomers such as (-)-hinokinin, (-)-dimethylmatairesinol and tetrahydrofuran-type lignans.

II. Research Reagents for Phytoestrogen Pharmacology and Structure-Activity Relationship (SAR) Studies

Control Tool for Dietary Lignan Assays

The parent skeleton secoisolariciresinol is the predominant natural phytoestrogen in flaxseeds, which is metabolized by human intestinal flora into enterodiol and enterolactone. As a fully methylated derivative, this compound acts as a dedicated control sample for structure-activity relationship (SAR) research.

Mechanism Research of Antitumor Activity

It is utilized in in vitro cellular and pharmacological assays related to antioxidant effects and inhibitory activity against estrogen-dependent tumors (breast cancer), to compare how methoxy-substituted structures alter the biological activities of lignans.

III. Reference Standards for Analysis and Detection of Natural Products

It can be used as a dedicated reference standard for qualitative and quantitative analysis of lignan natural products, compatible with GC-MS (Gas Chromatography-Mass Spectrometry) and HPLC (High-Performance Liquid Chromatography) detection systems. It is applied for quantitative determination and qualitative identification of lignan components in plant extracts, food products and biological samples.

This product is custom-synthesized. Please contact us if you have special specification requirements.

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