1,5-Pentanediol-CAS-111-29-5

Product Name:1,5-Pentanediol

CAS: 111-29-5

Pharmaceutical R&D Immunosuppression A potent immunosuppressant. It inhibits T-cell activation and the production of key cytokines like Interleukin-2. It is widely used in scientific research to prolong the survival of transplanted organs and as a tool molecule for studying the immune system.
Dermatological Treatment Its analogues (e.g., Pimecrolimus) have been developed for treating inflammatory skin conditions like atopic dermatitis (eczema).
Anti-cancer Research Studies have shown that Ascomycin and its analogue Tacrolimus can inhibit the growth, migration, and invasion of certain cancer cells, such as melanoma.
 Agricultural Application Fungicide As an agricultural antibiotic, it can effectively control various fungal diseases in crops, such as tomato gray mold, cucumber gray mold, and southern corn leaf blight.

 Major Application Fields

Leveraging its unique chemical structure and properties, 1,5-pentanediol plays important roles in several industrial sectors. Its applications span the polymer industry, solvent and additive systems, intermediate chemistry, and emerging fields.

Applications in the Polymer Industry

 Polyester and Polyether Synthesis

1,5-Pentanediol is a significant monomer for synthesizing high-performance polyester and polyether resins. During polycondensation reactions with dicarboxylic acids (such as adipic acid, terephthalic acid), it forms polyester segments with specific flexibility. Polyesters containing this five-carbon segment possess moderate glass transition temperatures and a good balance of mechanical properties, making them widely used in:

• Saturated and Unsaturated Polyester Resins: Used in fiberglass reinforced plastics, coatings, and adhesives.

• Oil-free Alkyd Resins: Used in high-performance coatings and surface finishes.

• Special Polyester Polyols: Used as precursors for polyurethane materials.

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