Basic information：
| Product name | 1,2-DIHEXADECANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)] SODIUM SALT |
| Synonym | DPPGSODIUM;L-ALPHA-PHOSPHATIDYL-DL-GLYCEROL,DIPALMITOYLSODIUMSALT;16:0PG(SODIUMSALT);1,2-DIHEXADECANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)]SODIUMSALT;1,2-DIPALMITOYL-SN-GLYCERO-3-[PHOSChemicalbookPHO-RAC-(1-GLYCEROL)](SODIUMSALT);1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-RAC-GLYCEROLSODIUMSALT;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLGLYCEROLSODIUM;l-α-phosphatidyl-dl-glycerol,dipalmitoyl |
| CAS No. | 67232-81-9 |
| MF | C38H76NaO10P |
| MW | 746.98 |
| Related categories | Pharmaceutical excipient; Lipid |
| Storage | Storage at -20℃ |
| Packaging | 500g/bag, 1kg/bag, 5kg/bag, 25kg/drum, can be also subpacked as customer’s request. |
| Product Manager | Cara Lee Email: Cara@coreychem.com |
Application:
1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt (DPPG-Na, CAS: 67232-81-9) is a synthetic anionic phospholipid widely used in liposomal drug delivery, biomembrane research, pharmaceutical excipients and cosmetics.
- Liposomal Drug Delivery (Core)
- Forms negatively charged, stable liposomes to prevent particle aggregation and membrane fusion, maintaining uniform particle size.
- Classic use in bupivacaine liposomes (EXPAREL) to form multivesicular structures for 72-hour long-acting sustained release.
- Used in amphotericin B liposomes to inhibit membrane fusion, enhancing stability and safety.
- Facilitates tumor-targeted delivery; negatively charged liposomes promote anticancer drug entry into cancer cells.
- Biomembrane & Research
- Constructs bacterial/mitochondrial inner membrane models to study membrane protein function and lipid-protein interactions.
- Applied in membrane biophysics, membrane protein crystallization and pulmonary surfactant research.
- Pharmaceutical Excipients & Formulations
- Acts as an injectable-grade emulsifier/stabilizer for lipid emulsions, microspheres and other nanoformulations.
- Used in nebulized inhalation formulations to mimic pulmonary surfactants and improve pulmonary delivery efficiency.
- Cosmetics & Others
- Functions as an emulsifier, thickener and humectant to enhance emulsion stability and skin feel.
- Utilized in biomedical imaging materials and gene delivery vector development.
🌡Storage:
protect from light, stored at -20℃.
Any interest, please contact product manager:Cara@coreychem
