Basic information：
| Product name | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE |
| Synonym | 3-sn-Phosphatidicacid,1,2-dipalmitoylmonosodiumsalt,L-β,γ-Dipalmitoyl-α-phosphatidicacidmonosodiumsalt;HexadecanoicAcid(R)-1-[(Phosphonooxy)Methyl]-1,2-ethanediylEster,MonosodiuMSalt;HexadecanoicAcid1,1′-[(1R)-1-[(Phosphonooxy)Methyl]-1,2-ethanediyChemicalbookl]EsterSodiuMSalt;MonosodiuM1,2-dipalMitoyl-sn-glycero-3-phosphate;DPPAL-4116;L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDICACID,SODIUMSALT;L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDICACID2NA;L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDICACIDMONOSODIUMSALT |
| CAS No. | 169051-60-9 |
| MF | C35H67Na2O8P |
| MW | 692.85 |
| Related categories | Pharmaceutical excipient; Lipid |
| Storage | Storage at 2-8℃ |
| Packaging | 1kg/bottle 5kg/bottle, 25kg/drum, can be also subpacked as customer’s request. |
| Product Manager | Cara Lee Email: Cara@coreychem.com |
Application:
1,2-Dipalmitoyl-sn-glycero-3-phosphate monosodium salt (DPPA) is anionic phospholipid, widely used in the construction of various liposomes and artificial membranes.
The application is as below:
- Liposome & Artificial Membrane Construction：Anionic phospholipid for liposomes, micelles, and artificial bilayers; mimics cell membranes to study fluidity, permeability, and membrane protein function.
- Drug Delivery System：Key liposome component encapsulating hydrophobic drugs and nucleic acids (siRNA/DNA); enhances stability, targeting, and bioavailability for mRNA vaccines and gene therapy.
- Cell Signaling Research：Activates MAPK cascade, binds Raf-1 to promote membrane translocation; acts as an intracellular pH sensor linking metabolism and membrane biogenesis.
- Membrane Biophysics Research：Studies membrane surface charge, protein-lipid interactions, cell fusion, and membrane fusion mechanisms.
- Cosmetics & Pharmaceutical Excipients：Emulsifier/stabilizer improving formulation stability and skin permeability; used in nanoemulsions and creams.
- Biosensors：Modifies electrode surfaces to construct biosensing interfaces for nucleic acid/protein detection.
- Pulmonary Surfactant Research：Mimics lung surfactant for neonatal respiratory distress syndrome studies.
🌡Storage:
protect from light, stored at 2-8℃.
Any interest, please contact product manager:Cara@coreychem
