| Product Name | 1-METHYL-1H-INDOLE-5-CARBOXYLIC ACID |
| Synonyms | 5-Carboxy-1-methyl-1H-indole;1-METHYLINDOLE-5-CARBOXYLIC ACID;1-METHYL-1H-INDOLE-5-CARBOXYLIC ACID;1-Methyl-5-indolecarboxylic Acid;1H-Indole-5-carboxylic acid, 1-methyl-;1-Methyl-1H-indole-5-carboxylicacid97%;1-Methyl-1H-indole-5-carboxylic acid 97% |
| CAS NO | 186129-25-9 |
| Purity | 96% |
| Appearance | White to light yellow Solid |
| MF | C10H9NO2 |
| MW | 175.18 |
| Contact | selina@coreychem.com |
1-Methyl-1H-indole-5-carboxylic acid (CAS: 186129-25-9) is an important indole-based intermediate widely used in pharmaceutical, agrochemical, and fine chemical research and development. It is generally not used as a final active ingredient but serves as a key building block in synthesis.
Functions and applications:
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Used as an intermediate in the synthesis of anticancer, anti-inflammatory, antiviral, antibacterial, and central nervous system (CNS) drug candidates.
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The N-1 methyl substitution improves molecular stability and lipophilicity, while the 5-carboxyl group enables further chemical transformations such as esterification, amidation, and coupling reactions, making it highly suitable for medicinal chemistry optimization.
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Applied in the design and development of indole derivatives during lead discovery and structure–activity relationship (SAR) studies.
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Used as a synthetic intermediate in agrochemical research, including insecticides, fungicides, and plant growth regulators.
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Employed in fine chemical synthesis and CRO/CDMO custom synthesis projects, as well as in the development of functional molecules and research compounds.
In summary, 1-methyl-1H-indole-5-carboxylic acid is a versatile and valuable indole building block for drug discovery, agrochemical development, and advanced chemical research.
Related product recommendations：
| Product Name | CAS |
| 3-Quinolinecarboxylic acid | 6480-68-8 |
| 1-methyl-1H-indole-5-carboxylic acid | 186129-25-9 |
| 1-Methyl-1H-indol-5-amine | 102308-97-4 |
| Methyl 5-methylindole-3-carboxylate | 227960-12-5 |
| 5-Fluoro-2-methylindole | 399-72-4 |
| 5-Fluoroindole | 399-52-0 |
| 5-Bromo-2-methylindole | 1075-34-9 |
| 5-Bromoindole-3-butyric acid | 13993-31-2 |
| 5-Fluoroindole-3-butyric acid | 319-72-2 |
| 5-Cyano-2-methylindole-3-acetic acid | 13218-36-5 |
| 5-Chloroindole | 17422-32-1 |
| 5-Hydroxyindole | 1953-54-4 |
| 5-Aminoindole | 5192-03-0 |
| 5-Methylindole | 614-96-0 |
| 5-Nitroindole | 6146-52-7 |
| 5-Benzyloxyindole | 1215-59-4 |
| DL-5-Hydroxytryptophan | 114-03-4 |
| 5-Methoxyindole | 1006-94-6 |
| 5-Piperidin-4-yl-1H-indole | 383861-22-1 |
| 5-Methoxyindole-3-butyric acid | 83696-90-6 |
| 5-Cyanoindole-1-acetic acid | 202124-67-2 |
| 3-(4′-Fluorobenzoyl)indole | 152807-26-6 |
| 3-(4-Fluorophenyl)-1-isopropyl-1H-indole-2-carbaldehyde | 101125-34-2 |
| 1H-Indole-2-carboxylicacid, 3-(4-fluorophenyl)-, ethyl ester | 93957-39-2 |
We specialize in the supply of indole-based compounds, offering a broad portfolio of high-quality intermediates and building blocks.
In addition to catalog products, we provide custom synthesis and scale-up services, supporting projects from early research to commercial production. With strong synthetic capabilities and flexible manufacturing solutions, we are able to meet diverse customer requirements in pharmaceutical, agrochemical, and fine chemical applications.
Contact us for more information: selina@coreychem.com
